43 days in South America & Mexico Itinerary

43 days in South America & Mexico Itinerary

Created using Inspirock trip itinerary planner

Make it your trip
Fly
1
Buenos Aires, Argentina
— 2 nights
Fly
2
Lima, Peru
— 2 nights
Fly
3
Cusco, Peru
— 2 nights
Bus to Ollantaytambo, Train to Machu Picchu
4
Machu Picchu, Peru
— 2 nights
Fly
5
Puerto Maldonado, Peru
— 1 night
Fly
6
Medellin, Colombia
— 5 nights
Fly
7
Cartagena, Colombia
— 4 nights
Drive
8
Santa Marta, Colombia
— 2 nights
Drive to Ernesto Cortissoz International Airport, Fly to Oaxaca
9
Oaxaca, Mexico
— 4 nights
Fly
10
Puerto Escondido, Mexico
— 10 nights
Fly to San Jose Cabo, Bus to Cabo San Lucas
11
Cabo San Lucas, Mexico
— 5 nights
Fly

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Buenos Aires, Argentina

— 2 nights

Queen of La Plata

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for nightlife, historic sites, and parks. Your trip includes some of its best attractions: explore the different monuments and memorials at Cemiterio de Recoleta, admire the architecture and history at Plaza de Mayo, admire the natural beauty at Parque 3 de Febrero, and take in the architecture and atmosphere at Catedral Primada.

Start your trip to Buenos Aires by creating a personalized itinerary on Inspirock.

Wellington, New Zealand to Buenos Aires is an approximately 17-hour flight. The time zone changes from New Zealand Standard Time to Argentina Standard Time, which is usually a -15 hour difference. In March, Buenos Aires is a bit warmer than Wellington - with highs of 29°C and lows of 20°C. Wrap up your sightseeing on the 3rd (Thu) to allow time to fly to Lima.

Things to do in Buenos Aires

Historic Sites · Shopping · Neighborhoods · Parks
Find places to stay Feb 28 — Mar 3:

Lima, Peru

— 2 nights

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Start off your visit on the 4th (Fri): examine the collection at Museo de Minerales Andres del Castillo, don't miss a visit to Plaza de Armas (Plaza Mayor), then take in the architecture and atmosphere at Museo Convento San Francisco y Catacumbas, and finally take in the spiritual surroundings of Basilica y Monasterio de Santo Domingo. Keep things going the next day: contemplate the long history of Huaca Pucllana and then take an in-depth tour of Museo Larco.

For ratings, traveler tips, photos, and other tourist information, read our Lima tour planner.

Getting from Buenos Aires to Lima by flight takes about 8 hours. Other options: drive; or take a bus. Due to the time zone difference, you'll gain 2 hours traveling from Buenos Aires to Lima. In March, daytime highs in Lima are 32°C, while nighttime lows are 24°C. Cap off your sightseeing on the 6th (Sun) early enough to catch the flight to Cusco.

Things to do in Lima

Historic Sites · Museums
Find places to stay Mar 3 — 6:

Cusco, Peru

— 2 nights

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
On the 6th (Sun), take in the local highlights with Walking tours. On the next day, get engrossed in the history at Museo Inka, then explore the ancient world of Sacsayhuaman, then steep yourself in history at Plaza de Armas, and finally explore the ancient world of Centro Historico De Cusco.

To see traveler tips, photos, maps, and tourist information, read our Cusco trip builder website.

Traveling by flight from Lima to Cusco takes 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Lima in March, you will find days in Cusco are little chillier (23°C), and nights are colder (9°C). Finish your sightseeing early on the 8th (Tue) to allow enough time to travel to Machu Picchu.

Things to do in Cusco

Tours · Historic Sites · Museums
Find places to stay Mar 6 — 8:

Machu Picchu, Peru

— 2 nights
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 8th (Tue): take in nature's colorful creations at Mandor and then contemplate the long history of Santuario Historico de Machu Picchu. Here are some ideas for day two: delve into the distant past at Winay Wayna and then take some stellar pictures from Intipuncu.

To see where to stay, more things to do, other places to visit, and other tourist information, read Machu Picchu trip planner.

Traveling by combination of bus and train from Cusco to Machu Picchu takes 4 hours. Alternatively, you can take a train; or drive. Wrap up your sightseeing on the 10th (Thu) early enough to fly to Puerto Maldonado.

Things to do in Machu Picchu

Historic Sites · Parks · Wildlife
Find places to stay Mar 8 — 10:

Puerto Maldonado, Peru

— 1 night
Puerto Maldonado sits at the confluence of the Tambopata and Madre de Dios Rivers in the Amazon rainforest.
Start off your visit on the 10th (Thu): explore the activities along Lago Sandoval. On the 11th (Fri), you'll have a packed day of sightseeing: stroll through Mariposario Tambopata and then tour the pleasant surroundings at Inkaterra Ecological Reserve.

For other places to visit, ratings, traveler tips, and other tourist information, you can read our Puerto Maldonado trip planner.

Traveling by flight from Machu Picchu to Puerto Maldonado takes 2.5 hours. Alternatively, you can do a combination of train and bus; or drive. In March, plan for daily highs up to 37°C, and evening lows to 26°C. Cap off your sightseeing on the 11th (Fri) early enough to travel to Medellin.

Things to do in Puerto Maldonado

Parks · Wildlife · Nature

Side Trip

Find places to stay Mar 10 — 11:

Medellin, Colombia

— 5 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Venture out of the city with trips to Piedra Del Penol (in Guatape) and Off-Road Tours (in Guarne). Next up on the itinerary: get the lay of the land with Walking tours, fly like a bird with a parasailing or paragliding tour, admire the natural beauty at Jardin Botanico de Medellin, and stroll around Parque Lleras.

To see traveler tips, photos, other places to visit, and more tourist information, refer to the Medellin travel itinerary planner.

Explore your travel options from Puerto Maldonado to Medellin with the Route module. Traveling from Puerto Maldonado in March, things will get a bit cooler in Medellin: highs are around 32°C and lows about 21°C. Finish your sightseeing early on the 17th (Thu) to allow enough time to fly to Cartagena.

Things to do in Medellin

Parks · Nature · Tours · Zoos & Aquariums

Side Trips

Find places to stay Mar 12 — 17:

Cartagena, Colombia

— 4 nights

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Cartagena is known for historic sites, museums, and nightlife. Your trip includes some of its best attractions: steep yourself in history at Walled City of Cartagena, don't miss a visit to Plaza de Bolivar, take an in-depth tour of Museo del Oro Zenu, and contemplate in the serene atmosphere at Convent of Santa Cruz de la Popa.

To see other places to visit, traveler tips, maps, and tourist information, read Cartagena trip itinerary maker tool.

Traveling by flight from Medellin to Cartagena takes 3 hours. Alternatively, you can drive; or take a bus. In March, Cartagena is somewhat warmer than Medellin - with highs of 37°C and lows of 29°C. Wrap up your sightseeing on the 21st (Mon) early enough to drive to Santa Marta.

Things to do in Cartagena

Historic Sites · Museums · Parks · Outdoors
Find places to stay Mar 17 — 21:

Santa Marta, Colombia

— 2 nights

America's Pearl

Many visitors begin their Santa Marta holiday, surrounded by urban clutter and heavy traffic, expecting little from the city in terms of historical importance.
Kick off your visit on the 22nd (Tue): identify plant and animal life at Wildlife Areas and then stroll around Parque de Los Novios. On your second day here, take in nature's colorful creations at Quinta de San Pedro Alejandrino and then enjoy the sand and surf at Playa Blanca.

To see photos, maps, ratings, and other tourist information, read our Santa Marta road trip tool.

Getting from Cartagena to Santa Marta by car takes about 3.5 hours. Other options: take a bus. Expect a daytime high around 39°C in March, and nighttime lows around 29°C. Finish up your sightseeing early on the 23rd (Wed) so you can catch the flight to Oaxaca.

Things to do in Santa Marta

Parks · Outdoors · Wildlife · Tours
Find places to stay Mar 21 — 23:

Oaxaca, Mexico

— 4 nights
Capital city of the eponymous state, Oaxaca relies heavily on its colonial charm, its core a maze of tree-shaded alleys flanked by photogenic mansions, government buildings, and old churches.
Oaxaca is known for museums, historic sites, and shopping. Your trip includes some of its best attractions: pause for some serene contemplation at Templo de Santo Domingo de Guzman, hunt for treasures at Mercado Benito Juárez, see the interesting displays at Museo de las Culturas de Oaxaca, and admire the natural beauty at Jardin Etnobotanico de Oaxaca.

To find reviews, other places to visit, ratings, and other tourist information, use the Oaxaca journey planner.

Use the Route module to find suitable travel options from Santa Marta to Oaxaca. The time zone changes from Colombia Standard Time (COT) to Central Standard Time (CST), which is usually a -1 hour difference. When traveling from Santa Marta in March, plan for slightly colder days in Oaxaca, with highs around 36°C, while nights are much colder with lows around 15°C. Finish your sightseeing early on the 28th (Mon) so you can fly to Puerto Escondido.

Things to do in Oaxaca

Historic Sites · Museums · Shopping · Parks
Find places to stay Mar 24 — 28:

Puerto Escondido, Mexico

— 10 nights
Puerto Escondido is a small port and tourist center in the municipality of San Pedro Mixtepec Distrito 22 in the Mexican state of Oaxaca. Get out of town with these interesting Puerto Escondido side-trips: Zipolite (Playa del Amor & Playa Zipolite) and Mazunte (Punta Cometa, Hridaya Yoga, &more). There's lots more to do: kick back and relax at Playa Zicatela, tour the pleasant surroundings at Playa Principal de Puerto Escondido, see majestic marine mammals with a dolphin and whale watching tour, and contemplate the waterfront views at Laguna Manialtepec.

To see other places to visit and tourist information, read Puerto Escondido trip planner.

Getting from Oaxaca to Puerto Escondido by flight takes about 3 hours. Other options: drive; or take a bus. Traveling from Oaxaca in March, plan for somewhat warmer nights in Puerto Escondido, with lows around 27°C. You will leave for Cabo San Lucas on the 7th (Thu).

Things to do in Puerto Escondido

Parks · Outdoors · Beaches · Nature

Side Trips

Find places to stay Mar 28 — Apr 7:

Cabo San Lucas, Mexico

— 5 nights
One of Mexico's premier vacation spots, Cabo San Lucas lures pleasure seekers with its trendy restaurant scene, raucous nightlife, and, of course, picture-perfect beaches.
Venture out of the city with trips to San Jose del Cabo (Enrique Bascon, Galeria de Arte & Sillvermoon Gallery). There's still lots to do: take in the dramatic natural features at El Arco de Cabo San Lucas, take in the waterfront activity at Marina Cabo San Lucas, relax and rejuvenate at some of the best spas, and cast your line with a fishing tour.

To find photos, traveler tips, reviews, and tourist information, use the Cabo San Lucas vacation maker site.

You can do a combination of flight and bus from Puerto Escondido to Cabo San Lucas in 10 hours. Alternatively, you can do a combination of bus and ferry; or drive. You'll gain 1 hour traveling from Puerto Escondido to Cabo San Lucas due to the time zone difference. Traveling from Puerto Escondido in April, expect little chillier with lows of 23°C in Cabo San Lucas. Wrap up your sightseeing by early afternoon on the 12th (Tue) to allow time for the flight back home.

Things to do in Cabo San Lucas

Parks · Outdoors · Beaches · Nature

Side Trip

Find places to stay Apr 7 — 12:

Mexico travel guide

4.5
Ruins · Beaches · Scuba & Snorkeling
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.